Blackburn BLACKBURN's innovation

Invented by professor Blackburn in 1973 Globesity is now the most important method of the obesity treatments. Blackburn proved that during the proteinous fast little quantities of amino acids can cause some light changes in the metabolic reaction and they are able to neutralize the negative azotic balance. So the dangers of a total empty stomach could be eliminated by ingesting some proteins without any carbon hydrates.

In his studies Blackburn identifies the exact amount of proteins which one individual has to take during the fasting phase to protect his noble mass that goes from 1.2 to 1.5 grams per Kilo of his ideal weight.

So a proteinous fast originates and keeps the azotic balance getting rid of the need to eat thanks to a state of ketosis which accompanies this process.

In the proteinous fast we have a reduction of the glucose with the consequent activation of the catabolism of the adipic triglycerides.

The lypoproteinlipase (LPL) hydrolyzes the triglycerides by converting them in fatty acids and glycerol. The glycerol is oxidized and then it develops into glucose in the liver. 40% of the produced fatty acids are directly employed in the muscle works.

Other 60% undergoes an hepatic β-oxidation producing the Acetyl Co-A. The successive condensation of two Acetyl Co-A molecules creates the acetic acid. This will be mostly converted in acetoacetate and beta-hydrobutyrate acid.

These three compounds are called ketone bodies.

The correct pancreatic functionality that is typical of no diabetic patients lets the successive reconversion of the Ketone bodies in Acetyl Co-A and their successive metabolization with low concentrations of insulin.

During the proteinous fasting the production of the ketone bodies has many advantages: they provide 25% of the energy that our body needs helping the brain with converting its energetic sources by using the free fatty acids and 80% ketone bodies for its metabolism. The ketone bodies circulate freely in our body and provide energy, they do not need of the transmembran proteins which enter the cellular membranes freely. In conclusion the proteinous fasting allows the full utilization of the energy coming from the adipose tissue by reducing it without damaging the lean mass.

Mechanism of action

The only contribution of proteins (1,2 g/kg in women and 1,5g/kg in men) which is a low calorie intake makes our body get them from its reserve stocks. After exhausting the stocks by converting them in glycogen, an hepatic gluconeogenesis starts and this will take 30% food that is indispensable for the cerebral process. Proteins are degraded on the hepatic basis creating ketone bodies through a ketosis process; these ketone bodies do a double action:

Energetic action: as energetic basis of the brain, which support up to 80% of his needs, with mind -altering effects (some antidepressive effects, an increase of the intellectual faculty and euphoria).

Anorexic action: the ketone bodies with the stimulation of the satiety centre located in the hypothalamus leads a physiological antihunger effect with the decreased sensation of appetite since the third day of the beginning of the diet.

A nearly total suppression of the glucides: with a drastic reduction of the glucides replaced by some specific vegetables such as: asparagus, spinaches, cucumbers, green beans, aubergines, salad, broccoli, pumpkins, leeks, Belgian salad. There is a quick loss of insulin which stops the reservation of fat and will produce the melting of it by lipolisys.

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